tailieunhanh - Báo cáo y học: "Lost in translation? The pursuit of lung-protective ventilation"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Lost in translation? The pursuit of lung-protective ventilation. | Available online http content 12 2 122 Commentary Lost in translation The pursuit of lung-protective ventilation Andrew T Jones Department of Intensive Care Medicine 1st Floor East Wing St Thomas s Hospital Westminster Bridge Road London SE1 7EH UK Corresponding author Andrew T Jones Published 31 March 2008 This article is online at http content 12 2 122 2008 BioMed Central Ltd Critical Care 2008 12 122 doi cc6828 See related research by The Irish Critical Care Trials Group http content 12 1 R30 Abstract Acute lung injury ALI and the acute respiratory distress syndrome ARDS remain important causes of morbidity and mortality in the critically ill patient with far-reaching short-term and long-term implications for individual patients and for healthcare providers. It is well accepted that mechanical ventilation can worsen lung injury potentially worsening systemic organ function and can thus impact on mortality in acute lung injury ALI ARDS. Unfortunately although the concept of minimizing such damage via lung-protective ventilatory strategies is widely acknowledged effective integration of such an approach into clinical practice remains more elusive. The study by the Irish Critical Care Trials Group published in the previous edition of Critical Care describes a 10-week real-life survey of all intensive care unit admissions across Ireland detailing for the first time the epidemiology of ALI ARDS in this population and elinieian s attempts to deliver lung-protective ventilation. The authors also report hypothesis-generating data on the implications of statin use in this population. The present commentary reviews aspects of this work with particular attention to the implementation of low-tidal-volume lung-protective ventilatory strategies in ALI ARDS. Firstly my congratulations to those at the Irish Critical Care Trials Group on their paper detailing the epidemiology and ventilatory management of ALI .