tailieunhanh - Báo cáo y học: " Alveolar recruitment can be predicted from airway pressure-lung volume loops: an experimental study in a porcine acute lung injury model"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Alveolar recruitment can be predicted from airway pressure-lung volume loops: an experimental study in a porcine acute lung injury model. | Available online http content 1 2 1 R7 Research Alveolar recruitment can be predicted from airway pressure-lung volume loops an experimental study in a porcine acute lung injury model Jacob Koefoed-Nielsen1 Niels Dahlsgaard Nielsen1 Anders J Kj rgaard2 and Anders Larsson1 1 Department of Anesthesia and Intensive Care Aarhus University Hospital Aalborg Hobrovej 18-22 DK-9000 Aalborg Denmark 2Department of Anesthesia and Intensive Care Aarhus University Hospital Arhus Norrebrogade 44 DK-8000 Arhus Denmark Corresponding author Jacob Koefoed-Nielsen koefoedjacob@ Received 30 Sep 2007 Revisions requested 17 Nov 2007 Revisions received 29 Nov 2007 Accepted 21 Jan 2008 Published 21 Jan 2008 Critical Care 2008 12 R7 doi cc6771 This article is online at http content 12 1 R7 2008 Koefoed-Nielsen et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Simple methods to predict the effect of lung recruitment maneuvers LRMs in acute lung injury ALI and acute respiratory distress syndrome ARDS are lacking. It has previously been found that a static pressure-volume PV loop could indicate the increase in lung volume induced by positive end-expiratory pressure PEEP in ARDS. The purpose of this study was to test the hypothesis that in ALI 1 the difference in lung volume AV at a specific airway pressure 10 cmH2O was chosen in this test obtained from the limbs of a PV loop agree with the increase in end-expiratory lung volume AEELV by an LRM at a specific PEEP 10 cmH2O and 2 the maximal relative vertical volume difference between the limbs maximal hysteresis total lung capacity MH TLC could predict the changes in respiratory compliance Crs EELV and partial pressures of