tailieunhanh - Báo cáo y học: "Diagnostic utility of the soluble triggering receptor expressed on myeloid cells-1 in bronchoalveolar lavage fluid from patients with bilateral lung infiltrates"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Diagnostic utility of the soluble triggering receptor expressed on myeloid cells-1 in bronchoalveolar lavage fluid from patients with bilateral lung infiltrates. | Available online http content 1 2 1 R6 Research Diagnostic utility of the soluble triggering receptor expressed on myeloid cells-1 in bronchoalveolar lavage fluid from patients with bilateral lung infiltrates Jin Won Huh1 Chae-Man Lim2 Younsuck Koh2 Yeon Mok Oh2 Tae Sun Shim2 Sang Do Lee2 Woo Sung Kim2 Dong Soon Kim2 Won Dong Kim2 and Sang-Bum Hong2 Department of Pulmonary and Critical Care Medicine Ilsan Paik Hospital Inje University 2240 Daehwa-dong Ilsanseo-gu Goyang-si Gyeonggi-do 411-706 Korea 2Division of Pulmonary and Critical Care Medicine Asan Medical Center College of Medicine University of Ulsan 388-1 Pungnap-dong Songpa-gu Seoul Korea Corresponding author Sang-Bum Hong sbhong@ Received 15 Sep 2007 Revisions requested 5 Nov 2007 Revisions received 5 Dec 2007 Accepted 19 Jan 2008 Published 19 Jan 2008 Critical Care 2008 12 R6 doi cc6770 This article is online at http content 12 1 R6 2008 Huh et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Background Differential diagnosis of patients with bilateral lung infiltrates remains a difficult problem for intensive care clinicians. Here we evaluate the diagnostic role of soluble triggering receptor expressed on myeloid cells-1 sTREM-1 in bronchoalveolar lavage BAL specimens from patients with bilateral lung infiltrates. Methods We conducted a prospective observational study on 80 patients with bilateral lung infiltrates with clinical suspicion of infectious pneumonia. Patients were categorized into three groups bacterial or fungal infection intracellular or viral infection and noninfectious inflammatory disease. sTREM-1 concentrations were measured and BAL fluid and Clinical Pulmonary Infection Score .