tailieunhanh - Báo cáo y học: "Effect of sepsis therapies on health-related quality of life."

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Effect of sepsis therapies on health-related quality of life. | Available online http content 12 1 109 Commentary Effect of sepsis therapies on health-related quality of life Sara E Erickson and Greg S Martin Division of Pulmonary Allergy and Critical Care Emory University School of Medicine Grady Memorial Hospital 49 Jesse Hill Jr Drive SE Atlanta GA 30303 USA Corresponding author Greg S Martin Published 22 January 2008 This article is online at http content 12 1 109 2008 BioMed Central Ltd Critical Care 2008 12 109 doi cc6215 See related research by Longo et al. http content 11 6 R128 Abstract Sepsis is one of the most common conditions encountered in the intensive care unit and is the 10th leading cause of death overall in the United States. Both long-term survival and health-related quality of life are reduced in survivors of sepsis yet there is little knowledge of the effect of sepsis-specific interventions on either long-term survival or health-related quality of life. The present article discusses the importance of studying health-related quality of life as it relates to sepsis management strategies particularly in the context of pharmacologic therapy with recombinant human activated protein C. Sepsis affects more than 750 000 patients each year in the United States it is the 10th leading cause of death and one of the leading causes for admission to the intensive care unit 1-4 . The estimated mortality from sepsis is 20-30 meaning that approximately 500 000 patients survive their septic episode annually in the United States alone 3 4 . What happens to these sepsis survivors Are they able to resume their lives and regular activities or does sepsis have far-reaching effects that extend beyond the hospitalization Ten years ago Quartin and colleagues were the first to show that sepsis has long-lasting effects and increases the risk of death up to 5 years after hospitalization for the septic episode 5 . Mounting evidence has since demonstrated that survivors of