tailieunhanh - Endourooncology New Horizons in Endourology - part 7

Tất cả các phân tích thống kê được thực hiện bằng cách sử dụng phần mềm thương mại sẵn có (StatView , Abacus khái niệm, Berkeley, CA, USA). Kiểm tra chi-bình phương đánh giá mối tương quan giữa các thông số trước và sau phẫu thuật. | 104 T. Uchida et al. treatment PSA nadir and the first of three consecutive PSA increases. Prostate needle biopsies were performed in all patients at 6 months postoperatively. All patients had at least three PSA determinations during follow-up. None of the patients received androgen deprivation after HIFU or other anticancer therapy before documentation of a biochemical failure. Statistical Analysis All statistical analyses were performed using commercially available software StatView Abacus Concepts Berkeley CA USA . The chi-squared test assessed the correlation between preoperative and postoperative parameters. The distributions of biochemical disease-free survival rates were calculated according to the Kaplan-Meier method and the log-rank test was used to compare curves for groups. Age clinical stage Gleason score volume of the prostate neoadjuvant hormone therapy and pretreatment serum PSA was analyzed to estimate the prognostic relevance in a multivariate Cox proportionalhazards regression model. All p values less than reflected statistically significant differences. Results Seventy-one patients were treated in one HIFU session 13 patients in two sessions and 1 patient in three sessions for a total of 100 procedures in 85 patients sessions per patient . The reasons for repeat HIFU treatments were as follows six patients were retreated because of short on 2sec or long off 8 to 12 sec intervals four patients were retreated for residual tumor two patients were hemilaterally treated on the right or left lobe of the prostate two patients needed a repeat session to treat the whole prostate because of larger prostate size and ml and one patient was retreated because of machine trouble. The median operating time and hospitalization was 150 min range 30 to 356 min and days range 3 to 20 . A gradual reduction in prostate volume occurred in all patients. The gland size decreased from an initial volume of mL range mL to a final .

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