tailieunhanh - Báo cáo y học: "The risk for bloodstream infections is associated with increased parenteral caloric intake in patients receiving parenteral nutrition"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: The risk for bloodstream infections is associated with increased parenteral caloric intake in patients receiving parenteral nutrition. | Available online http content 11 5 R114 Open Access Research The risk for bloodstream infections is associated with increased parenteral caloric intake in patients receiving parenteral nutrition Sharmila Dissanaike1 Marilyn Shelton2 Keir Warner2 and Grant E O Keefe2 1Harborview Medical Center 325 9th Ave Seattle WA 98104 USA 2Department of Surgery Texas Tech University Health Sciences Center 3601 4th St Lubbock TX 79430 USA Corresponding author Sharmila Dissanaike Received 12 Apr 2007 Revisions requested 17 May 2007 Revisions received 6 Sep 2007 Accepted 24 Oct 2007 Published 24 Oct 2007 Critical Care 2007 11 R114 doi cc6167 This article is online at http content 11 5 R114 2007 Dissanaike et al. licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by 20 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. See related commentary by Griffiths http content 11 6 1 76 Abstract Background Patients receiving total parenteral nutrition TPN are at high risk for bloodstream infections BSI . The notion that intravenous calories and glucose lead to hyperglycemia which in turn contributes to BSI risk is widely held but is unproven. We therefore sought to determine the role that hyperglycemia and parenteral calories play in the development of BSI in hospitalized patients receiving TPN. Methods Two hundred consecutive patients initiated on TPN between June 2004 and August 2005 were prospectively studied. Information was collected on patient age sex admission diagnosis baseline laboratory values intensive care unit ICU status and indication for TPN. Patients in the ICU were managed with strict glycemic control whereas control on the general ward was more liberal. The maximum blood glucose level over each 8-hour period was .

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