tailieunhanh - Báo cáo y học: "Usefulness of C-reactive protein in monitoring the severe community-acquired pneumonia clinical course"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Usefulness of C-reactive protein in monitoring the severe community-acquired pneumonia clinical course. | Available online http content 11 4 R92 Research Usefulness of C-reactive protein in monitoring the severe community-acquired pneumonia clinical course Luis Coelho Pedro Póvoa Eduardo Almeida Antero Fernandes Rui Mealha Pedro Moreira and Henrique Sabino Unidade de Cuidados Intensivos Hospital Garcia de Orta Almada Portugal Corresponding author Luis Coelho luismiguelcoelhol 6@ Received 5 Jun 2007 Revisions requested 4 Jul 2007 Revisions received 10 Aug 2007 Accepted 28 Aug 2007 Published 28 Aug 2007 Critical Care 2007 11 R92 doi cc61 05 This article is online at http content 11 4 R92 2007 Coelho et al. licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by 20 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Background The aim of the present study was to evaluate the C-reactive protein level the body temperature and the white cell count in patients after prescription of antibiotics in order to describe the clinical resolution of severe community-acquired pneumonia. Methods A cohort of 53 consecutive patients with severe community-acquired pneumonia was studied. The C-reactive protein levels body temperature and white cell count were monitored daily. Results By day 3 a C-reactive protein level times the initial level was a marker of poor outcome sensitivity specificity . Patients were divided according to their C-reactive protein patterns of response to antibiotics into fast response slow response nonresponse and biphasic response. About 96 of patients with a C-reactive protein pattern of fast response and 74 of patients with a slow response pattern survived whereas those patients with the patterns of nonresponse and of biphasic response had a mortality rate of 100 and 33 respectively P . On day 3 of .