tailieunhanh - Báo cáo y học: "Activated protein C: cost-effective or costly"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Activated protein C: cost-effective or costly? | Available online http content 11 5 164 Commentary Activated protein C cost-effective or costly Savtaj Singh Brar1 and Braden J Manns2 3 1 Department of Surgery University of Calgary and Calgary Health Region Calgary Alberta T2L 2K8 Canada 2Department of Medicine University of Calgary and Calgary Health Region Calgary Alberta T2L 2K8 Canada 3Department of Community Health Sciences University of Calgary and Calgary Health Region Calgary Alberta T2L 2K8 Canada Corresponding author Braden J Manns Published 10 September 2007 This article is online at http content 11 5 164 2007 BioMed Central Ltd Critical Care 2007 11 164 doi cc6090 See related research by Dhainaut et al. http content 11 5 R99 Abstract The authors offer a commentary on the study by Dhainaut et al. on the cost-effectiveness of activated protein C in severe sepsis. Using data from real world conditions the results of this economic evaluation are consistent with previous analyses and highlight the need for real world investigations of new health technologies in critical care. Dhainaut and colleagues in the French study group PREMISS Protocole en Réanimation d EvaluationMedico-economique d une Innovation dans le Sepsis Severe report the results of the first economic evaluation of recombinant human activated protein C APC in patients with severe sepsis performed using real world effectiveness data 1 . Economic evaluations in critical care medicine are relatively new but given the expense of health care within an intensive care unit ICU their use is likely to become more common 2 . The unique nature of this analysis is that it estimated effectiveness using real world patients treated before and after the availability of APC rather than basing effectiveness on the findings of the study Protein C Worldwide Evaluation in Severe Sepsis PROWESS a randomized control trial RCT which was used for all previous economic evaultions of APC 4-8

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