tailieunhanh - báo cáo khoa học: "Relationship between oxygen supply and cerebral blood flow assessed by transcranial Doppler and near – infrared spectroscopy in healthy subjects during breath – holding"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Relationship between oxygen supply and cerebral blood flow assessed by transcranial Doppler and near – infrared spectroscopy in healthy subjects during breath – holding | Journal of NeuroEngineering and Rehabilitation Methodology BioMed Central Open Access Relationship between oxygen supply and cerebral blood flow assessed by transcranial Doppler and near - infrared spectroscopy in healthy subjects during breath - holding Filippo Molinari 1 William Liboni2 Gianfranco Grippi2 and Emanuela Negri2 Address 1Biolab Dipartimento di Elettronica Politecnico di Torino Torino Italy and . Neurologia Presidio Sanitario Gradenigo Torino Italy Email Filippo Molinari - William Liboni - Gianfranco Grippi - EmanuelaNegri - qualita@ Corresponding author Published 19 July 2006 Received 20 July 2005 Journal of NeuroEngineering and Rehabilitation 2006 3 16 doi 1743-0003-3-16 Accepted I9 July 2006 This article is available from http content 3 1 16 2006 Molinari et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Breath - holding BH is a suitable method for inducing cerebral vasomotor reactivity VMR . The assessment of VMR is of clinical importance for the early detection of risk conditions and for the follow-up of disabled patients. Transcranial Doppler ultrasonography TCD is used to measure cerebral blood flow velocity CBFV during BH whereas near-infrared spectroscopy NIRS measures the concentrations of the oxygenated O2Hb and reduced CO2Hb hemoglobin. The two techniques provide circulatory and functional-related parameters. The aim of the study is the analysis of the relationship between oxygen supply and CBFV as detected by TCD and NIRS in healthy subjects performing BH. Methods 20 healthy subjects 15 males and 5 females age 33 years underwent TCD