tailieunhanh - Báo cáo y học: " Hodgkin’s lymphoma presenting with heart failure: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Hodgkin’s lymphoma presenting with heart failure: a case report | Amirimoghaddam et al. Journal of Medical Case Reports 2010 4 14 http content 4 1 14 JOURNALOF medical ÌỤr case REPORTS CASE REPORT Open Access Hodgkin s lymphoma presenting with heart failure a case report Zeinab Amirimoghaddam1 Malihe Khoddami1 Nahid Dehghan Nayeri2 Somayeh Molaee2 Abstract Introduction Cardiac involvement in malignant lymphoma is one of the least investigated subjects in oncology. This article reports a case of cardiac involvement in Hodgkin s lymphoma which presented as heart failure. Case presentation We report the case of an 8-year-old Afghan girl with Hodgkin s lymphoma. The disease presented with systemic signs and symptoms including abdominal distension weakness pallor chills fever generalized edema hepatosplenomegaly and generalized lymphadenopathy as well as signs of heart failure. Test results showed a rare form of heart metastasis. Conclusion We report a case of Hodgkin s lymphoma with metastasis to the heart detected premortem. Although the involvement of the heart in a malignancy is relatively common premortem detection is unusual and only few studies have reported it in the literature. Introduction Cardiac involvement in malignant lymphoma is one of the least investigated subjects in oncology 1 . Cardiac metastases are found in 20 to 25 of patients with lymphoma 2 3 . Studies by Roberts et al. and Cains et al. reported that 9 of all cardiac tumors are related to lymphoma 3 4 . Some authors have described primary cardiac lymphomas presenting with pericardial effusion 5 arrhythmias and heart failure 6 . Echocardiography is known to be a sensitive method for the diagnosis of cardiac involvement in p atients with lymphoma. The pattern of cardiac involvement varies with different types of lymphoma suggesting that different pathologic types of lymphoma may have different mechanisms of metastasis to the heart. Diffused myocardial infiltration documented by echocardiography has rarely been described as a .