tailieunhanh - Báo cáo hóa học: " Carbon composite micro- and nano-tubes-based electrodes for detection of nucleic acids"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Carbon composite micro- and nano-tubes-based electrodes for detection of nucleic acids | Prasek et al. Nanoscale Research Letters 2011 6 385 http content 6 1 385 o Nanoscale Research Letters a SpringerOpen Journal NANO EXPRESS Open Access Carbon composite micro- and nano-tubes-based electrodes for detection of nucleic acids 1 2 3 3 2 2 2 Jan Prasek Dalibor Huska Ondrej Jasek Lenka Zajickova Libuse Trnkova Vojtech Adam Rene Kizek and Jaromir Hubalek1 Abstract The first aim of this study was to fabricate vertically aligned multiwalled carbon nanotubes MWCNTs . MWCNTs were successfully prepared by using plasma enhanced chemical vapour deposition. Further three carbon composite electrodes with different content of carbon particles with various shapes and sizes were prepared and tested on measuring of nucleic acids. The dependences of adenine peak height on the concentration of nucleic acid sample were measured. Carbon composite electrode prepared from a mixture of glassy and spherical carbon powder and MWCNTs had the highest sensitivity to nucleic acids. Other interesting result is the fact that we were able to distinguish signals for all bases using this electrode. Background In the last two decades nanomaterials in the form of nanotubes and nanowires have begun to be reported as promising materials for wide field of applications 1 2 . Such materials could be also used for fabrication of miniaturized electrodes. The nanostructured electrodes could be fabricated using several techniques. The easiest fabrication technique is to use a mixture of nanomaterial as filler with a suitable vehicle which could be deposited on the electrode substrate using screen-printing drop-coating dip-coating spraying etc. 3 4 . The disadvantage of these nanocomposition-based electrodes is the irreproducible electrode surface with undefined active electrode area. The reproducible nanostructured electrode surface could be fabricated using lithography as a common tool for microelectronics devices implementation 5 anodization process for nanorods or .