tailieunhanh - Handbook of Clinical Neurology

James Parkinson described Parkinson’s disease in his memorable Essay on the Shaking Palsy in 1817. Since then, and particularly in recent years, there has been tremendous progress in our understanding of this complex and fascinating neurological disorder. Briefly, we have learned that it is not only manifest by motor symptoms but also that there is a whole range of non-motor features, including autonomic, psychiatric, cognitive and sensory impairments. We now know how to distinguish better clinically between Parkinson’s disease and the various parkinsonian syndromes. Likewise, it is now well established that in this disorder not only the substantia nigra but many other central as well as. | M MAUK HANDBOOK OF CLINICAL NEUROLOGY Serio Edimrsc Michael J. AMINOFF. EK ANựỉlSBOII IK. DICK F. SWA AB 84 PARKIXM vs DISEASE AND RELATED DISORDERS PART II Edited by WILLIAM - KOLLER ELDAD MELAMED Obituary William C. Koller MD PhD 1945-2005 William C. Koller died unexpectedly on October 3 2005 in Chapel Hill North Carolina while this volume which he was co-editing was in preparation. Bill was born in Milwaukee on July 12 1945 where he graduated with a BS degree from Marquette University in1968. He went on to Northwestern University in Chicago where he received a Masters degree in pharmacology in 1971 a PhD in pharmacology in 1974 and an MD in 1976. After completing his internship and residency at Rush Presbyterian St. Luke s Medical Center in Chicago he held positions at the Rush Medical College University of Illinois Chicago VA Hines VA and Loyola University. In 1987 he was appointed Professor and Chairman of Neurology at the University of Kansas Medical Center where he remained until 1999 when he moved to the University of Miami and became the National Research Director for the National Parkinson Foundation. He subsequently moved on to direct the Movement Disorders clinical program at the Mount Sinai Medical Center in New York and then to the University of North Carolina where he laid the foundation for yet another superb clinical and academic program. Bill was a world-renowned neurologist who specialized in Parkinson s disease essential tremor and related disorders. He published more than 270 peer-reviewed manuscripts over 160 review papers and numerous books. His research interests included the epidemiology and experimental therapeutics of parkinsonism and essential tremor and his work contributed enormously to the current treatment of these disorders. His collaborations were worldwide and many current experts in movement disorders worked with him at one time or another. He was a Fellow of the American Academy of Neurology Treasurer of the Movement .