tailieunhanh - Báo cáo y học: "Human endogenous retrovirus-FRD envelope protein (syncytin 2) expression in normal and trisomy 21-affected placenta"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: "Human endogenous retrovirus-FRD envelope protein (syncytin 2) expression in normal and trisomy 21-affected placenta. | Retrovirology BioMed Central Short report Open Access Human endogenous retrovirus-FRD envelope protein syncytin 2 expression in normal and trisomy 21-affected placenta André Malassiné1 2 5 Jean-Louis Frendo1 2 3 5 Sandra Blaise4 Karen Handschuh1 2 Pascale Gerbaud1 2 5 Vassilis Tsatsaris1 2 5 Thierry Heidmann4 5 and Danièle Evain-Brion 1 2 5 Address 1INSERM U767 4 avenue de l Observatoire 75006 Paris France 2Université Paris Descartes Faculté des Sciences Pharmaceutiques et Biologiques 4 avenue de l Observatoire 75006 Paris France 3CNRS Paris F-75006 France 4Unité des Rétrovirus Endogènes et Eléments Rétroĩdes des Eucaryotes Supérieurs UMR 8122 CNRS Institut Gustave Roussy 39 rue Camille Desmoulins 94805 Villejuif France and 5PremUP Paris France Email André Malassiné - Jean-Louis Frendo - Sandra Blaise - Karen Handschuh - Pascale Gerbaud - Vassilis Tsatsaris - Thierry Heidmann - heidmann@ Danièle Evain-Brion - Corresponding author Published 23 January 2008 Received 3 October 2007 Accepted 23 January 2008 Retrovirology 2008 5 6 doi 1742-4690-5-6 This article is available from http content 5 1 6 2008 Malassiné et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Human trophoblast expresses two fusogenic retroviral envelope proteins the widely studied syncytin I encoded by HERV-W and the recently characterized syncytin 2 encoded by HERV-FRD. Here we studied syncytin 2 in normal and Trisomy 21-affected placenta associated with abnormal trophoblast differentiation. .