tailieunhanh - Báo cáo y học: "Impairment of alternative splice sites defining a novel gammaretroviral exon within gag modifies the oncogenic properties of Akv murine leukemia virus"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: "Impairment of alternative splice sites defining a novel gammaretroviral exon within gag modifies the oncogenic properties of Akv murine leukemia virus. | Retrovirology BioMed Central Open Access Impairment of alternative splice sites defining a novel gammaretroviral exon within gag modifies the oncogenic properties of Akv murine leukemia virus Annette Balle Sorensen1 6 Anders H Lund1 7 Sandra Kunder2 Leticia Quintanilla-Martinez2 Jorg Schmidt3 Bruce Wang4 Matthias Wabl5 and Finn Skou Pedersen 1 Address Department of Molecular Biology University of Aarhus Denmark institute of Pathology GSF-National Research Center for Environment and Health Neuherberg Germany 3Department of Comparative Medicine GSF-National Research Center for Environment and Health Neuherberg Germany 4Picobella Burlingame CA USA 5Department of Microbiology and Immunology University of California-San Francisco San Francisco CA USA 6The State and University Library Universitetsparken DK-8000 Aarhus C Denmark and 7Biotech Research and Innovation Centre BRIC University of Copenhagen Ole Maaloes Vej 5 DK-2200 Copenhagen N Denmark Email Annette Balle Sorensen - abs@ Anders H Lund - Sandra Kunder - Leticia Quintanilla-Martinez - quintanilla-fend@ Jorg Schmidt - Bruce Wang - bruce@ Matthias Wabl - mutator@ Finn Skou Pedersen - fsp@ Corresponding author Published 6 July 2007 Received 7 March 2007 Retrovirology 2007 4 46 doi 1742-4690-4-46 Accepted 6 July 2007 This article is available from http content 4 1 46 2007 Sorensen et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Mutations of an alternative splice donor site located within the gag region has previously been shown to broaden the pathogenic potential of the T-lymphomagenic gammaretrovirus

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