tailieunhanh - Báo cáo y học: "Physiological properties of astroglial cell lines derived from mice with high (SAMP8) and low (SAMR1, ICR) levels of endogenous retrovirus"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: "Physiological properties of astroglial cell lines derived from mice with high (SAMP8) and low (SAMR1, ICR) levels of endogenous retrovirus. | Retrovirology BioMed Central Research Physiological properties of astroglial cell lines derived from mice with high SAMP8 and low SAMR1 ICR levels of endogenous retrovirus Boe-Hyun Kim1 Harry C Meeker2 Hae-Young Shin1 Jae-Il Kim2 Byung-Hoon Jeong1 Eun-Kyoung Choi1 Richard I Carp2 and Yong-Sun Kim 1 Open Access Address 1Ilsong Institute of Life Science Hallym University 1605-4 Gwanyang-dong Dongan-gu Anyang Gyeonggi-do 431-060 South Korea and 2New York State Institute for Basic Research in Developmental Disabilities Staten Island NY 10314 USA Email Boe-Hyun Kim - bhkim@ Harry C Meeker - Hae-Young Shin - shilysea@ Jae- Il Kim - Byung-Hoon Jeong - bhjeong@ Eun-Kyoung Choi - ekchoi@ Richard I Carp - Yong-Sun Kim - yskim@ Corresponding author Published 25 November 2008 Received 30 August 2008 Accepted 25 November 2008 Retrovirology 2008 5 104 doi p This article is available from http content 5 1 104 2008 Kim et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Previous studies have reported that various inbred SAM mouse strains differ markedly with regard to a variety of parameters such as capacity for learning and memory life spans and brain histopathology. A potential cause of differences seen in these strains may be based on the fact that some strains have a high concentration of infectious murine leukemia virus MuLV in the brain whereas other strains have little or no virus. To elucidate the effect of a higher titer of endogenous retrovirus in astroglial cells