tailieunhanh - PLANTS THAT FIGHT CANCER - PART 4

Xuất hiện (Hình ) gốc: 6-17 m cao, với vỏ màu đỏ cho thấy một underbark mịn màng và màu xám uốn lượn, thân dày, ngành bất thường lớn. Lá: 10-28 cm dài 3-7 tờ rơi hình bầu dục hoặc elip, mỗi 2,5-5 cm dài. Hoa: nhỏ, kín đáo, với 3-5 cánh hoa màu xanh lục, nở hoa kéo dài cành. | 84 Spiridon E. Kintzios et al. Bursera simaruba Bursera Burseraceae Cytotoxic Antitumor Location Central and northern South America. Appearance Figure Stem 6 17 m high with reddish bark that reveal a smooth and sinuous gray underbark thick trunk large irregular branches. Leaves 10 28 cm long with 3 7 oval or elliptic leaflets each 2 5 5 cm long. Flowers small inconspicuous with 3 5 greenish petals blooming in elongate racemes. In bloom Winter. Part used stem leaves. Active ingredients lignansp. deoxypodophyllotoxin beta-peltatin methyl ether picro-beta-peltatin methyl ether and dehydro-beta-peltatin methyl ether. Documented target cancers lymphocytic leukemia human epidermoid carcinoma of the nasopharynx. Lignans deoxypodophyllotoxin KB PS test systems 5 - desmethoxydeoxypodophyllotoxin morelensin KB test system . Sapelins A and B PS system. Further details Related compounds The stem of Bursera permollis contains four cytotoxic lignans deoxypodophyllotoxin beta-peltatin methyl ether picro-beta-peltatin methyl ether and dehydro-beta-peltatin methyl ether Wickramaratne et al. 1995 . Deoxypodophyllotoxin and another lignan 5 -desmethoxydeoxypodophyllotoxin were also isolated from the Figure Bursera. Terrestrial plant species with anticancer activity 85 dried exudate of B. morelensis Jolad et al. 1977b B. microphylla also contains deoxypodophyllotoxin Bianchi et al. 1968 . The leaves of B. klugii contain non-polar substances such as sapelins A and B which showed activity against two test systems the P-388 lymphocytic leukemia 3PS and the human epidermoid carcinoma of the nasopharynx 9KB Jolad et al. 1977a . The isolation and identification from Burseraceae are reported. The existence of lignans with antitumor activity in B. schlechtendalii has been reported McDoniel et al 1972 . References Bianchi E. Caldwell . and Cole . 1968 Antitumor agents from Bursera microphylla Burseraceae I. Isolation and characterization of deoxypodophyllotoxin. J. Pharm. Sci. 57