tailieunhanh - Burns Regenerative Medicine and Therapy - part 7

chúng tôi thực hiện nghiên cứu này để điều tra ảnh hưởng của MEBO sửa chữa và chữa lành các tổn thương giác mạc và vai trò của các loại thuốc khác cũng. Kết quả xác minh rằng MEBO rõ ràng là vượt trội so với các thuốc khác, ngoại trừ tương đồng trong huyết thanh trong việc thúc đẩy làm lành vết thương trong khi không có điểm vàng rõ ràng | we performed this study to investigate the effect of MEBO on repairing and healing of corneal defect and the roles of other drugs as well. The results verified that MEBO is obviously superior to other medications except for homologous serum in promoting wound healing while no obvious corneal macula was formed posthealing under slitlamp microscopic examination. The pharmacological mechanisms of MEBO with respect to its role of promoting healing of corneal wounds also became understood as follows 1 Composed of a macromolecular sticky base MEBO has an affinity to tissue protein at the wound site. The application of MEBO to the wound may serve as a bridge to directly stimulate and induce cell division and migration in an orderly manner that promotes wound healing. 2 MEBO contains various nutrients necessary for wound healing. For example glucose is an obvious energy source. Vitamins and organic acids which are related to the maintenance of tissue metabolism and proliferation of connective tissues may directly support local nutritional needs thereby preventing scar formation 6 . Zinc and enzymes may accelerate epithelial repair 7 . Protein as the basic element of the cell membrane may support the growth differentiation and regulation of cells. 3 MEBO promotes the formation of a unique integrated automatic drainage circulation system which corrects for local dysfunctional metabolism and circulation resulting from injury. The base ingredients contained in MEBO absorb metabolic products from the wound and then transport them to the outer layer of the ointment. Meanwhile active ingredients of the ointment continuously penetrate into the wound to renew the supply of ingredients necessary for tissue repair. The automatic microparticle transportation and processing of emulsification and dispersion are considered as the main measure for the treatment of injured avascular tissue 8 . 4 Obaculactone contained in MEBO offers properties of anti-inflammation detumescence analgesic .