tailieunhanh - Child Health Genomics: An Investment in Canada's Future

A recent report 5 by Dr. K. Kellie Leitch to the Minister of Health highlighted three major areas of focus to improve child health. Genomics will play a critical role in addressing two of these areas: obesity and healthy lifestyles, and mental health and chronic illness. Improving child health through genomics directly aligns with the goals of the National Science and Technology strategy, focusing our S&T investment in the high priority area of health and related life sciences and technologies, which is identified as one of four areas of focus for investment. 6 Canadian health organizations including the Canadian Medical. | Genome Canada - Strategic Research Themes Child Health Genomics An Investment in Canada s Future Prepared by the Child Health Genomics Working Group Janet Rossant Theme Leader The Hospital for Sick Children Toronto Guy Rouleau Theme Leader CHU Sainte-Justine Montreal Ron Lafrenière Theme Coordinator CHUM Research Centre Montreal Consultants The Agricola Group George Brook David Brook Ken Lawless Contributors Stephanie Atkinson McMaster University Hamilton Denise Avard Université de Montréal Phillip Awadalla CHU Sainte-Justine Montreal Gwen Burrows Sick Kids Research Institute Toronto Jayne Danska The Hospital for Sick Children Toronto Terry Delovitch Juvenile Diabetes Research Foundation Judah A. Denburg McMaster University Jessica Dupuis Juvenile Diabetes Research Foundation Jan Friedman University of British Columbia Vancouver Thomas J. Hudson Ontario Institute for Cancer Research Toronto Agnes V. Klein Health Canada Ottawa Bartha M. Knoppers Université de Montréal Emile Levy Université de Montréal Alex MacKenzie The Children s Hospital of Eastern Ontario Ottawa David Malkin The Hospital for Sick Children Toronto Alain Moreau CHU Sainte-Justine Montreal Constantin Polychronakos McGill University Montreal Daniel Sinnett Université de Montréal Peter Szatmari McMaster University Hamilton July 4th 2008 Executive Summary Many of the most complex and devastating diseases of childhood have a strong genetic basis. The Canadian genomics community is poised to make substantial contributions in the understanding prediction and treatment of these illnesses enabling better long term health outcomes for children in five key areas of impact 1. Childhood cancer 2. Neurodevelopmental diseases autism mental retardation schizophrenia ADHD 3. Auto-immune inflammatory and allergic disease type 1 diabetes asthma 4. Obesity and type 2 diabetes 5. Birth defects New genomic technologies are changing the way we analyze diseases from one gene and one patient at a time to population-wide .