tailieunhanh - Báo cáo khoa học: "Attributable mortality of Acinetobacter baumannii: no longer a controversial issue"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Attributable mortality of Acinetobacter baumannii: no longer a controversial issue. | Available online http content 11 3 134 Commentary Attributable mortality of Acinetobacter baumannii no longer a controversial issue Matthew E Falagas1 2 3 and Petros I Rafailidis1 3 1Alfa Institute of Biomedical Sciences Athens Greece 2Department of Medicine Tufts University School of Medicine Boston Massachusetts USA 3Department of Medicine Henry Dunant Hospital Athens Greece Corresponding author Matthew E Falagas Published 31 May 2007 This article is online at http content 11 3 134 2007 BioMed Central Ltd Critical Care 2007 11 134 doi cc5911 Abstract There has been controversy regarding the mortality directly attributed to Acinetobacter baumannii infections. Data from six case-control studies have been recently added to the literature regarding the attributable mortality of A. baumannii infections during the past months. The information from these studies added to the previous knowledge on this issue provides evidence that A. baumannii infections are indeed associated with increased mortality. In addition there is relevant evidence from studies examining the effect of inappropriate treatment on mortality specifically inappropriate treatment of A. baumannii infections has been associated with excess mortality. We believe that the accumulated data suggest that attributable mortality due to A. baumannii infections should no longer be a controversial issue. The efforts of the scientific community interested in this pathogen should therefore be directed to the development and introduction of new antibiotics effective against multidrug-resistant and pandrug-resistant A. baumannii as well as the implementation of infection control measures that may help us in the control of the increasing problem of A. baumannii infections. Infections due to Acinetobacter baumannii have been frequently considered by clinicians and researchers not to be associated with considerable mortality 1 . Indeed A. baumannii has been placed in the