tailieunhanh - Báo cáo khoa học: "The metabolic and renal effects of adrenaline and milrinone in patients with myocardial dysfunction after coronary artery bypass graftin"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: The metabolic and renal effects of adrenaline and milrinone in patients with myocardial dysfunction after coronary artery bypass grafting. | Available online http content 11 2 R51 Research The metabolic and renal effects of adrenaline and milrinone in patients with myocardial dysfunction after coronary artery bypass grafting Matthias Heringlake1 Marit Wernerus1 Julia Grunefeld1 Stephan Klaus2 Hermann Heinze1 Matthias Bechtel3 Ludger Bahlmann4 Jochen Poeling5 and Julika Schon1 Department of Anesthesiology Universitat zu Lubeck D-23538 Lubeck Germany 2Department of Anesthesiology Herz-Jesu Krankenhaus Munster-Hiltrup D - 48165 Munster Germany 3Department of Cardiac Surgery Universitat zu Lubeck D-23538 Lubeck Germany 4Department of Anesthesiology Krankenhaus Weser-Egge D - 37671 Hoxter Germany 5Department of Cardiac Surgery Schuchtermann-Klinik D - 4921 4 Bad Rothenfelde Germany Corresponding author Matthias Heringlake Heringlake@ Received 20 Mar 2007 Accepted 30 Apr 2007 Published 30 Apr 2007 Critical Care 2007 11 R51 doi cc5904 This article is online at http content 11 2 R51 2007 Heringlake et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Myocardial dysfunction necessitating inotropic support is a typical complication after on-pump cardiac surgery. This prospective randomized pilot study analyzes the metabolic and renal effects of the inotropes adrenaline and milrinone in patients needing inotropic support after coronary artery bypass grafting CABG . Methods During an 18-month period 251 patients were screened for low cardiac output upon intensive care unit ICU admission after elective isolated CABG surgery. Patients presenting with a cardiac index CI of less than liters minute per square meter upon ICU admission - despite adequate mean arterial titrated with noradrenaline or