tailieunhanh - Báo cáo khoa học: " Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis. | Available online http content 11 2 R49 Research Cytokine profiles as markers of disease severity in sepsis a multiplex analysis Fernando A Bozza1 2 Jorge I Salluh3 4 André M Japiassu1 2 5 Marcio Soares4 Edson F Assis6 Rachel N Gomes6 Marcelo T Bozza7 Hugo C Castro-Faria-Neto6 and Patricia T Bozza6 1ICU Instituto de Pesquisa Clinica Evandro Chagas Fundaọão Oswaldo Cruz Av Brasil 4365 Rio de Janeiro Brazil 2ICU Hospital Universitário Clementino Fraga Filho Universidade Federal do Rio de Janeiro Rio de Janeiro Brazil 3ICU Hospital Barra D Or Av. Ayrton Senna 2541 Rio de Janeiro 22775-001 Brazil 4ICU Instituto Nacional do Câncer Rio de Janeiro Brazil 5ICU Hospital Quinta D Or R. Almirante Baltazar 435 Rio de Janeiro 20941-150 Brazil 6Laboratório de Imunofarmacologia Departamento de Fisiologia e Farmacodinâmica IOC Fundaọão Oswaldo Cruz Av Brasil 4365 Rio de Janeiro 21045-900 Brazil 7Departamento de Imunologia Instituto de Microbiologia Universidade Federal do Rio de Janeiro Rio de Janeiro RJ 21941-590 Brazil Corresponding author Patricia T Bozza pbozza@ Received 3 Jan 2007 Revisions requested 16 Feb 2007 Revisions received 3 Apr 2007 Accepted 21 Apr 2007 Published 21 Apr 2007 Critical Care 2007 11 R49 doi cc5783 This article is online at http content 11 2 R49 2007 Bozza et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction The current shortage of accurate and readily available validated biomarkers of disease severity in sepsis is an important limitation when attempting to stratify patients into homogeneous groups in order to study pathogenesis or develop therapeutic interventions. The aim of the present study was to determine the cytokine profile .