tailieunhanh - Báo cáo y học: "Churg-Strauss syndrome following cessation of allergic desensitization vaccination: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Churg-Strauss syndrome following cessation of allergic desensitization vaccination: a case report. | Masjedi et al. Journal of Medical Case Reports 2010 4 188 http content 4 1 188 jA CASE REPORTS CASE REPORT Open Access Ch urg-Strauss syndrome following cessation of allergic desensitization vaccination a case report Mohammad Reza Masjedi Saeid Fallah Tafti Ali Cheraghvandi Nader Fayazi Firouzeh Talischi and Bahareh Mokri Abstract Introduction Churg-Strauss syndrome is a vasculitis of medium to small sized vessels. Diagnosis is mainly clinical with findings of asthma eosinophilia rhinosinusitis and signs of vasculitis in major organs. Case presentation We present a case of a 19-year-old Persian male who developed signs and symptoms of this syndrome related to hyposensitization treatments for allergy control. Conclusions No unifying etiology for the disease can be presented as it is found associated with environmental factors medications infections and is even considered a variant of asthma with predisposition to vasculitic involvement. Therefore it is important to recognize this disease and be aware of underdiagnosis because of emphasis on pathologic evidence. Here we present a case of allergic desensitization causing Churg-Strauss syndrome in the absence of other known factors. Introduction Churg-Strauss syndrome CSS is a vasculitis of medium to small sized muscular arteries and veins. CSS was first described in 13 patients with deadly asthma who had the combination symptoms of asthma and eosinophilia rhinosinusitis and signs of vasculitis in the heart pericardium the nervous and gastroenteric systems and other vital organs 1 . Even though some consider allergic asthma rhinosinusitis and eosinophilia separate of the CSS most reports consider this vasculitis a disease by itself or a variant of asthma which occurs from immune system involvement such as with the use of medications like leukotrienes or sudden withdrawal of oral steroids 2 3 . They also consider environmental factors significant in development of primary .