tailieunhanh - Báo cáo y học: " Acute lyme infection presenting with amyopathic dermatomyositis and rapidly fatal interstitial pulmonary fibrosis: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Acute lyme infection presenting with amyopathic dermatomyositis and rapidly fatal interstitial pulmonary fibrosis: a case report. | Nguyen et al. Journal of Medical Case Reports 2010 4 187 http content 4 1 187 jA CASE REPORTS CASE REPORT Open Access Acute lyme infection presenting with amyopathic dermatomyositis and rapidly fatal interstitial pulmonary fibrosis a case report Hien Nguyen 1 Connie Le2 and Hanh Nguyen3 Abstract Introduction Dermatomyositis has been described in the setting of lyme infection in only nine previous case reports. Although lyme disease is known to induce typical clinical findings that are observed in various collagen vascular diseases to our knowledge we believe that our case is the first presentation of acute lyme disease associated with amyopathic dermatomyositis which was then followed by severe and fatal interstitial pulmonary fibrosis only two months later. Case presentation We present a case of a 64-year-old African-American man with multiple medical problems who was diagnosed with acute lyme infection after presenting with the pathognomonic rash and confirmatory serology. In spite of appropriate antimicrobial therapy for lyme infection he developed unexpected amyopathic dermatomyositis and then interstitial lung disease. Conclusions This case illustrates a potential for lyme disease to produce clinical syndromes that may be indistinguishable from primary connective tissue diseases. An atypical and sequential presentation dermatomyositis and interstitial lung disease of a common disease lyme infection is discussed. This case illustrates that in patients who are diagnosed with lyme infection who subsequently develop atypical muscular respiratory or other systemic complaints the possibility of severe rheumatological and pulmonary complications should be considered. Introduction Dermatomyositis has been described in the setting of lyme infection in only nine previous case reports. Our case is unique in the rapidity and severity of the subsequent fatal interstitial lung disease ILD . In spite of a link of dermatomyositis