tailieunhanh - Báo cáo khoa học: "Cortisol levels in cerebrospinal fluid correlate with severity and bacterial origin of meningitis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Cortisol levels in cerebrospinal fluid correlate with severity and bacterial origin of meningitis. | Available online http content 11 2 R41 Research Cortisol levels in cerebrospinal fluid correlate with severity and bacterial origin of meningitis Michal Holub1 2 Ondrej Beran1 2 Olga Dzupova2 3 Jarmila Hnyková1 Zdenka Lacinová4 Jana Príhodová2 Bohumír Prochazka5 and Miroslav Helcl2 Open Access 13rd Department of Infectious and Tropical Diseases of First Faculty of Medicine Charles University in Prague Budínova 2 CZ-1 80 81 Prague Czech Republic 2Department of Infectious Diseases University Hospital Bulovka Budínova 2 CZ-180 81 Prague Czech Republic 3Department of Infectious Diseases of Third Faculty of Medicine Charles University in Prague Budínova 2 CZ-180 81 Prague Czech Republic 43rd Medical Department - Department of Endocrinology and Metabolism of the First Faculty of Medicine Charles University in Prague U nemocnice 1 CZ-128 08 Prague Czech Republic 5Department of Biostatistics National Institute of Health ỗrobárova 48 CZ-100 42 Prague Czech Republic Corresponding author Michal Holub Received 22 Dec 2006 Revisions requested 22 Feb 2007 Revisions received 16 Mar 2007 Accepted 27 Mar 2007 Published 27 Mar 2007 Critical Care 2007 11 R41 doi cc5729 This article is online at http content 11 2 R41 2007 Holub et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Outcomes following bacterial meningitis are significantly improved by adjunctive treatment with corticosteroids. However little is known about the levels and significance of intrathecal endogenous cortisol. The aim of this study was to assess cortisol as a biological and diagnostic marker in patients with bacterial meningitis. Methods Forty-seven consecutive patients with bacterial .