tailieunhanh - Báo cáo y học: "Pleural aspergillosis complicated by recurrent pneumothorax: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Pleural aspergillosis complicated by recurrent pneumothorax: a case report. | Zhang et al. Journal of Medical Case Reports 2010 4 180 http content 4 1 180 jA CASE REPORTS CASE REPORT Open Access Pleural aspergillosis complicated by recurrent pneumothorax a case report Weihua Zhang 1 Ye Hu1 Liang an Chen1 Jie Gao2 and Lixin Xie 1 Abstract Introduction Pneumothorax as the first symptom of pleural aspergillosis is rare. Case presentation A 31-year-old asthmatic Chinese man presented with recurrent spontaneous pneumothorax and underwent lobectomy due to persistent air leakage. Aspergillus was detected histopathologically in the visceral pleural cavity. He was treated with itraconazole at 200 mg a day and nine months later he had no recurrent pneumothorax or aspergillus infection. Conclusion Recurrent pneumothorax may be a rare manifestation of aspergillus infection. Aspergillus species infection should be considered in the differential diagnosis of recurrent pneumothorax patients particularly those with chronic lung disease. Introduction Aspergillus spp. are ubiquitous fungi that are acquired by inhalation of airborne spores and may cause a variety of clinical lung syndromes. The severity of lung aspergillosis depends upon immune status and the presence of underlying lung disease. The manifestations range from invasive pulmonary aspergillosis in severely immunocompromised patients to chronic necrotizing aspergillosis in patients with chronic lung disease and or mildly compromised immune systems. Aspergilloma is primarily seen in patients with cavitary lung disease while acute bronchopulmonary aspergillosis ABPA is a hypersensitivity disease of the lungs that almost always affects patients with asthma or cystic fibrosis. In this paper we report a rare case of a patient who had multiple blebs recurrent pneumothorax and pleura that was infected by aspergillus with clinical features that were different from those described in the literature 1 . Case presentation A 31-year-old Chinese man was referred for