tailieunhanh - Báo cáo khoa học: "Skeletal muscle oxygen saturation does not estimate mixed venous oxygen saturation in patients with severe left heart failure and additional severe sepsis or septic shock"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Skeletal muscle oxygen saturation does not estimate mixed venous oxygen saturation in patients with severe left heart failure and additional severe sepsis or septic shock. | Available online http content 11 1 R6 Research Skeletal muscle oxygen saturation does not estimate mixed venous oxygen saturation in patients with severe left heart failure and additional severe sepsis or septic shock Matej Podbregar and Hugon Mozina Open Access Clinical Department for Intensive Care Medicine University Clinical Centre Zaloska 7 1000 Ljubljana Slovenia Corresponding author Matej Podbregar Received 13 Oct 2006 Revisions requested 22 Nov 2006 Revisions received 30 Nov 2006 Accepted 16 Jan 2007 Published 16 Jan 2007 Critical Care 2007 11 R6 doi cc5153 This article is online at http content 11 1 R6 2007 Podbregar and Mozina licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Low cardiac output states such as left heart failure are characterized by preserved oxygen extraction ratio which is in contrast to severe sepsis. Near infrared spectroscopy NIRS allows noninvasive estimation of skeletal muscle tissue oxygenation StO2 . The aim of the study was to determine the relationship between StO2 and mixed venous oxygen saturation SvO2 in patients with severe left heart failure with or without additional severe sepsis or septic shock. Methods Sixty-five patients with severe left heart failure due to primary heart disease were divided into two groups groups A n 24 and B n 41 included patients without and with additional severe sepsis septic shock respectively. Thenar muscle StO2 was measured using NIRS in the patients and in 15 healthy volunteers. Results StO2 was lower in group A than in group B and in healthy volunteers 58 13 90 7 and 84 4 respectively P . StO2 was higher in group B than in healthy volunteers P . In group A .