tailieunhanh - Báo cáo khoa học: "Effect of mode of hydrocortisone administration on glycemic control in patients with septic shock: a prospective randomized trial"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Effect of mode of hydrocortisone administration on glycemic control in patients with septic shock: a prospective randomized trial. | Available online http content 11 1 R21 Research Effect of mode of hydrocortisone administration on glycemic control in patients with septic shock a prospective randomized trial Pekka Loisa1 Ilkka Parviainen2 Jyrki Tenhunen3 Seppo Hovilehto4 and Esko Ruokonen2 Department of Intensive Care Paijat-Hame Central Hospital Keskussairaalankatu 7 FI 15850 Lahti Finland department of Intensive Care Kuopio University Hospital . Box 1 777 FI 70211 Kuopio Finland department of Intensive Care Tampere University Hospital . Box 2000 FI 33521 Tampere Finland department of Intensive Care South Carelian Central Hospital Valto Kakelan katu 1 FI 53130 Lappeenranta Finland Corresponding author Pekka Loisa Received 18 Oct 2006 Revisions requested 24 Nov 2006 Revisions received 1 Dec 2006 Accepted 16 Feb 2007 Published 16 Feb 2007 Critical Care 2007 11 R21 doi cc5696 This article is online at http content 11 1 R21 2007 Loisa et al. licensee BioMed Central Ltd This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Low-dose hydrocortisone treatment is widely accepted therapy for the treatment of vasopressor-dependent septic shock. The question of whether corticosteroids should be given to septic shock patients by continuous or by bolus infusion is still unanswered. Hydrocortisone induces hyperglycemia and it is possible that continuous hydrocortisone infusion would reduce the fluctuations in blood glucose levels and that tight blood glucose control could be better achieved with this approach. Methods In this prospective randomized study we compared the blood glucose profiles insulin requirements amount of nursing workload needed and shock reversal in 48 septic shock patients who received .