tailieunhanh - Báo cáo y học: " Cholangiocarcinoma presenting as hemobilia and recurrent iron-deficiency anemia: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Cholangiocarcinoma presenting as hemobilia and recurrent iron-deficiency anemia: a case report | Ahmad et al. Journal of Medical Case Reports 2010 4 133 http content 4 1 133 .Ịpv CASE REPORTS CASE REPORT Open Access Ch olangiocarcinoma presenting as hemobilia and recurrent iron-deficiency anemia a case report Saif S Ahmad 1 Faisal TM Basheer2 Saad F Idris2 Radhakrishnan Hariraj3 Rajarathnam Mathialagan3 and Andrew Douds3 Abstract Introduction Iron-deficiency anemia is a relatively common presenting feature of several gastrointestinal malignancies. However cholangiocarcinoma has rarely been reported as an underlying cause. The association of cholangiocarcinoma with the rare clinical finding of hemobilia is also highly unusual. To our knowledge this is the first case report of cholangiocarcinoma presenting with acute hemobilia and chronic iron-deficiency anemia. Case presentation We report the case of a Caucasian 84-year-old woman presenting with recurrent severe iron-deficiency anemia who was eventually diagnosed with intra-hepatic cholangiocarcinoma following an acute episode of hemobilia. A right hepatectomy was subsequently performed with curative intent and our patient has now fully recovered. Conclusion This is a rare example of hemobilia and chronic iron-deficiency anemia in association with cholangiocarcinoma. We suggest that a diagnosis of cholangiocarcinoma should be considered in patients who present with iron-deficiency anemia of unknown cause particularly in the presence of abnormal liver function. Introduction Iron-deficiency anemia is a relatively common presenting feature of several gastrointestinal malignancies. However cholangiocarcinoma has rarely been reported as an underlying cause. Hemobilia describes blood loss from the biliary tract. Its association with cholangiocarcinoma is very uncommon. We describe the case of a patient presenting with recurrent severe iron-deficiency anemia who after significant delay was eventually diagnosed with intra-hepatic cholangiocarcinoma following an acute .