tailieunhanh - Báo cáo khoa học: "Microdialysis shows metabolic effects in skin during fluid resuscitation in burn-injured patients"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Microdialysis shows metabolic effects in skin during fluid resuscitation in burn-injured patients. | Available online http content 10 6 R172 Research Microdialysis shows metabolic effects in skin during fluid resuscitation in burn-injured patients Anders Samuelsson1 Ingrid Steinvall2 and Folke Sjoberg1 2 3 Department of Intensive Care Linkoping University Hospital 581 85 Linkoping Sweden 2The Burn Unit Department of Hand and Plastic Surgery Linkoping University Hospital 581 85 Linkoping Sweden 3Faculty of Health Sciences Department of Biomedicine and Surgery Linkoping University Hospital 581 85 Linkoping Sweden Corresponding author Anders Samuelsson Received 5 Sep 2006 Revisions requested 2 Oct 2006 Revisions received 31 Oct 2006 Accepted 13 Dec 2006 Published 13 Dec 2006 Critical Care 2006 10 R172 doi cc5124 This article is online at http content 10 6 R1 72 2006 Samuelsson et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Established fluid treatment formulas for burn injuries have been challenged as studies have shown the presence of tissue hypoxia during standard resuscitation. Such findings suggest monitoring at the tissue level. This study was performed in patients with major burn injuries to evaluate the microdialysis technique for the continuous assessment of skin metabolic changes during fluid resuscitation and up to four days postburn. Methods We conducted an experimental study in patients with a burn injury as represented by percentage of total body surface area burned TBSA of more than 25 in a university eight-bed burns intensive care unit serving about million inhabitants. Six patients with a median TBSA percentage of 59 range to 90 and nine healthy controls were examined by intracutaneous MD in which .

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