tailieunhanh - báo cáo khoa học: " Human genomics and preparedness for infectious threats"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Human genomics and preparedness for infectious threats | Genome Medicine Commentary Human genomics and preparedness for infectious threats Nicole F Dowling Marta Gwinn and Alison Mawlet Addresses Office of Public Health Genomics National Center for Chronic Disease Prevention and Health Promotion Centers for Disease Control and Prevention Atlanta GA 30333 USA. National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention Atlanta GA 30333 USA. Correspondence Nicole F Dowling. Email ndowling@ Abstract Public health preparedness requires effective surveillance of and rapid response to infectious disease outbreaks. Inclusion of research activities within the outbreak setting provides important opportunities to maximize limited resources to enhance gains in scientific knowledge and ultimately to increase levels of preparedness. With rapid advances in laboratory technologies banking and analysis of human genomic specimens can be conducted as part of public health investigations enabling valuable research well into the future. Introduction Despite major progress toward understanding infectious agents and controlling their spread new and evolving infectious diseases - as well as old diseases in new contexts -continue to pose threats to humans worldwide. In 1992 the Institute of Medicine published an influential report calling attention to the emergence and re-emergence of human pathogens as a consequence of such factors as evolutionary changes in infectious agents and their human and non-human hosts alterations in host behaviors and travel and naturally occurring and man-made shifts in ecology geography and environment 1 . During the following decade renewed concern about microbial threats to health spurred new investments in scientific research and public health infrastructure. In 2003 the Institute of Medicine published a report entitled Microbial Threats to Health which highlighted the need for a global approach to preparedness 2 . That same year the severe acute respiratory .