tailieunhanh - Báo cáo khoa học: " Clinical review: Update of avian influenza A infections in humans"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Clinical review: Update of avian influenza A infections in humans. | Available online http content 11 2 209 Review Clinical review Update of avian influenza A infections in humans Christian Sandrock1 and Terra Kelly2 School of Medicine University of California Davis Sacramento CA 95817 USA 2School of Veterinary Medicine University of California Davis Sacramento CA 95817 USA Corresponding author Christian Sandrock cesandrock@ Published 22 March 2007 This article is online at http content 11 2 209 2007 BioMed Central Ltd Critical Care 2007 11 209 doi cc5675 Abstract Influenza A viruses have a wide host range for infection from wild waterfowl to poultry to humans. Recently the cross-species transmission of avian influenza A particularly subtype H5N1 has highlighted the importance of the non-human subtypes and their incidence in the human population has increased over the past decade. During cross-species transmission human disease can range from the asymptomatic to mild conjunctivitis to fulminant pneumonia and death. With these cases however the risk for genetic change and development of a novel virus increases heightening the need for public health and hospital measures. This review discusses the epidemiology host range human disease outcome treatment and prevention of cross-transmission of avian influenza A into humans. Introduction Human influenza pandemics over the last 100 years have been caused by H1 H2 and H3 subtypes of influenza A viruses. More recently avian influenza virus subtypes that is H5 H7 have been found to directly infect humans from their avian hosts. The recent emergence host expansion and spread of a highly pathogenic avian influenza HPAI H5N1 subtype in Asia have heightened concerns globally both in regards to mortality from HPAI H5N1 infection in humans and the potential of a new pandemic. This paper will review the current human infections with avian influenza and their public health and medical implications. Influenza A viruses Influenza A B and C are the most .