tailieunhanh - Báo cáo khoa học: "Blood glucose measurements in the critically ill: more than just a blood draw"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Blood glucose measurements in the critically ill: more than just a blood draw. | Available online http content 10 6 178 Commentary Blood glucose measurements in the critically ill more than just a blood draw Frank M Brunkhorst1 and Hans G Wahl2 Department of Anesthesiology and Intensive Care Medicine Friedrich-Schiller University Erlanger Allee 07747 Jena Germany institute for Clinical Chemistry and Laboratory Medicine Klinikum Ludenscheid Paulmannshoher Str. 58515 Ludenscheid Germany Corresponding author Frank M Brunkhorst Published 7 December 2006 Critical Care 2006 10 178 doi cc5110 This article is online at http content 10 6 178 2006 BioMed Central Ltd See related research by Corstjens et al. http content 10 5 R135 Abstract A crucial determinant for the success of intensive insulin therapy in critically ill patients is the frequent and accurate measurement of blood glucose values with immediate feedback of results. In general therefore this is achieved by point-of-care testing raising the question of the best way of monitoring blood glucose. Corstjens and coworkers in the previous issue of Critical Care demonstrate that in spite of good correlation to conventional laboratory glucose assessment absolute glucose levels may differ systematically. This commentary reviews the problems of glucose measurements arising from matrix effects interferences and the use of different assays. Intensive insulin therapy in critically ill patients In the preceding issue of Critical Care Corstjens and coworkers 1 investigated three different methods of glucose measurements. While data about the beneficial effects of normoglycemia in critically ill patients are conflicting and inconsistent 2 3 there is no doubt about the importance of accurate glucose measurements to achieve glycemic control without increased risk of hypoglycemia. Similar to the results from the Diabetes Control and Complications Trial which showed increasing frequency of hypoglycemia after tight glycemic control to .