tailieunhanh - Báo cáo khoa học: "AIP or ARDS"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: AIP or ARDS? | Available online http content 10 5 423 Letter AIP or ARDS Not just semantics Navneet Singh Department of Pulmonary Medicine Postgraduate Institute of Medical Education and Research Sector-12 Chandigarh-160012 India Corresponding author Navneet Singh navneetchd@ Published 29 September 2006 This article is online at http content 10 5 423 2006 BioMed Central Ltd Critical Care 2006 10 423 doi cc5003 See related research by Kao et al. http content 10 4 R106 I read with interest the article by Kao and colleagues 1 in which the authors investigated the role of open lung biopsy in patients with early-stage acute respiratory distress syndrome ARDS of suspected non-infectious origin. A point that merits attention is the need to differentiate between ARDS and acute interstitial pneumonia AIP . AIP is a rapidly progressive idiopathic interstitial pneumonia characterized by the presence of an organizing form of diffuse alveolar damage on histopathological examination of lung specimens. Although the histological pattern is indistinguishable from that found in ARDS the term AIP is reserved for cases of unknown cause 2 . In fact exclusion of a precipitating or etiological agent which is usually identifiable in patients with ARDS is one of the diagnostic criteria for AIP. The mortality from AIP is about 70 and is higher than that from ARDS 3 . Although there are no established therapies for AIP parenteral corticosteroids often at high doses are used frequently. Recently Suh and colleagues 4 reported survival rates of 80 in a small series of ten patients with AIP all of whom required mechanical ventilation with a median positive end-expiratory pressure of 11 cmH2O and underwent open lung biopsy on median hospital day 4 . In these patients high-dose corticosteroid pulse therapy had been initiated on median hospital day after respiratory infection had been ruled out by means of an aggressive diagnostic workup including .

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