tailieunhanh - Báo cáo khoa học: "What is a pressure–volume curve"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: What is a pressure–volume curve? | Available online http content 10 4 156 Commentary What is a pressure-volume curve Laurent Brochard Réanimation Médicale AP-HP Hôpital Henri Mondor Université Paris XII INSERM U651 Créteil France Corresponding author Laurent Brochard Published 10 August 2006 Critical Care 2006 10 156 doi cc5002 This article is online at http content 10 4 156 2006 BioMed Central Ltd Abstract The pressure-volume PV curve is a physiological tool proposed for diagnostic or monitoring purposes during mechanical ventilation of acute respiratory distress syndrome. The reduction in compliance measured by the PV curve and the different inflection points on the curve are considered interesting markers of the severity of and the levels of opening and closing pressures. Tracing a curve however may in itself influence the degree of opening or distension of the lung and interpretation of the curve has to take this effect into account. In some individuals tracing the curve may even have moderate hemodynamic effects. Fortunately on average most of these effects are transient or negligible and do not invalidate the PV curve measurement. The pressure-volume PV curve is a diagnostic or monitoring technique proposed soon after the initial description of acute respiratory distress syndrome ARDS 1 . The PV curve was really identified as a potentially important tool however by Matamis and colleagues 2 who described the relationship between alterations in respiratory mechanics and the stage of acute lung injury. The PV curve is usually traced from the elastic equilibrium lung volume that corresponds either to the functional residual capacity or to the end-expiratory lung volume. The end-expiratory lung volume can be greater than the residual capacity in the case of air trapping or of ventilation with positive end-expiratory pressure PEEP . The classic shape of the PV curve in ARDS patients is more or less sigmoidal with a general slope . .

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