tailieunhanh - Báo cáo y học: "Salmonella pyomyositis complicating sickle cell anemia: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Salmonella pyomyositis complicating sickle cell anemia: a case report. | Wong et al. Journal of Medical Case Reports 2010 4 198 http content 4 1 198 Ws CASE REPORTS CASE REPORT Open Access Salmonella pyomyositis complicating sickle cell anemia a case report Vanessa KWong 1 Maxine E Lissack2 Tom DTurmezei3 and Jenny A Maitland2 Abstract Introduction Pyomyositis is a bacterial infection of skeletal muscle and a rare complication of sickle cell anemia. It may present a difficult problem in diagnosis leading to delay in appropriate treatment and development of complications including abscess formation and osteomyelitis. Case presentation We report the case of a 44-year-old Afro-Caribbean woman with homozygous sickle cell disease who presented with chest crisis and later developed pyomyositis of her hip and pelvic muscles. Salmonella agbeni was isolated from blood cultures and magnetic resonance imaging confirmed the diagnosis in this case. It is noteworthy of this case that there were no antecedent signs of gastroenteritis. Drainage was not appropriate and she was treated with intravenous antibiotics for six weeks. Conclusions Focal Salmonella infections are uncommon in soft tissue. Pyomyositis should be considered in patients with sickle cell anemia that continue to have muscle pain and high fevers despite initial management of their sickle cell crisis. Radiological imaging particularly magnetic resonance imaging is a crucial tool in establishing the diagnosis. Introduction Pyomyositis is a purulent infection of skeletal muscle that can rapidly lead to abscess formation 1 . It usually occurs in association with damaged muscle and impaired host defenses. Pyomyositis usually presents with fever and muscle pain often in the lower extremity 2 . The most common causative organism is Staphylococcus aureus which gives classic pyomyositis 3 . The disease is a rare complication of sickle cell anemia with the diagnosis made even more difficult by the similarity of symptoms to a sickle cell crisis. We .