tailieunhanh - Báo cáo y học: "Giant renal oncocytoma: a case report and review of the literatur"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Giant renal oncocytoma: a case report and review of the literature. | Akbulut et al. Journal of Medical Case Reports 2010 4 52 http content 4 1 52 CASE REPORTS CASE REPORT Open Access Giant renal oncocytoma a case report and review of the literature Sami Akbulut 1 Ayhan Senol2 Bahri Cakabay1 and Arsenal Sezgin3 Abstract Introduction Renal oncocytomas are benign neoplasms derived from cells of the distal renal tubule and comprise 5 to 7 of primary renal neoplasms. Oncocytomas are mostly asymptomatic and the majority of tumors are discovered incidentally. In this case report we present a case of a patient with a giant oncocytoma arising from her left kidney. Case presentation We describe a 25-year-old Turkish woman who was admitted to our hospital with abdominal pain and a 3-year palpable abdominal mass which was found present since her second pregnancy. Examination revealed a 15 X 20-cm mass in her abdominal cavity. Computed tomography revealed a mass with regular outlines measuring 18 X 11 X 12 cm associated with the left kidney and causing marked hydroureteronephrosis. We excised the mass and performed a left nephrectomy on our patient. The immunohistopathology of the mass was consistent with renal oncocytoma. No local or distant metastasis was seen at 6 months postoperatively. Conclusion To the best of our knowledge this is the second largest renal oncocytoma described in the English language literature. This is also the first reported giant oncocytoma that presented during pregnancy. Introduction Oncocytomas are benign nonurothelial epithelial tumors that constitute 5 to 7 of primary renal neoplasms. Classically an oncocytoma is a solid mass that develops in the renal parenchyma and has a central fibrous scar 1 2 . Most are asymptomatic at presentation and are discovered only incidentally during evaluation of non-urological problems but hematuria and pain occur in a minority of documented cases 3 . Case presentation A 25-year-old Turkish woman was admitted to our hospital in October .