tailieunhanh - Báo cáo khoa học: "Optimizing neurologic prognosis after cardiac arrest"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Optimizing neurologic prognosis after cardiac arrest. | Available online http content 10 6 171 Commentary Optimizing neurologic prognosis after cardiac arrest David Tirschwell Harborview Medical Center University of Washington School of Medicine 325 Ninth Avenue Box 359775 Seattle WA 98104-2499 USA Corresponding author David Tirschwell tirsch@ Published 14 November 2006 This article is online at http content 10 6 171 2006 BioMed Central Ltd See related research by Rech et al. http content 10 5 R133 Abstract Neurologic disability is a feared outcome of resuscitation from cardiac arrest. The study by Rech and colleagues in the previous issue of Critical Care describes the use of neuron-specific enolase to inform an early prognosis in patients who survived in-hospital cardiac arrest. In their study none of the patients had a DNR order and there was no limitation of life support. As a result 10 of patients remained in a vegetative state at 6 months a higher percentage than in other recent studies. The existence of a population of patients in which all are fully supported without withholding care or withdrawal of care may represent an important research opportunity. High neuron-specific enolase levels have been reported in patients that awoke and seem to occur in studies with a higher percentage of patients in a vegetative state at follow-up more uniform support . If a comprehensive set of clinical electrophysiological biochemical and imaging measures could be obtained in a uniform manner in a cohort of patients without limitations in care a more objective set of comprehensive prognostic indicators could be obtained. A focused international consortium is called for. Neurologic disability is a feared outcome of resuscitation from cardiac arrest. The study by Rech and colleagues in the previous issue of Critical Care describes the use of neuronspecific enolase NSE to inform an early prognosis in 43 patients who survived for more than 12 hours after resuscitation from .