tailieunhanh - Báo cáo y học: "Massive hemoptysis and deep venous thrombosis presenting in a woman with Hughes-Stovin syndrome: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài:Massive hemoptysis and deep venous thrombosis presenting in a woman with Hughes-Stovin syndrome: a case report | Al-Jahdali Journal of Medical Case Reports 2010 4 109 http content 4 1 109 jA CASE REPORTS CASE REPORT Open Access Massive hemoptysis and deep venous thrombosis presenting in a woman with Hughes-Stovin syndrome a case report Hamdan Al-Jahdali Abstract Introduction Hughes-Stovin syndrome is a very rare disease with fewer than 30 cases reported in the literature. The disease is thought to be a variant of Behcet s disease and is defined by the presence of pulmonary artery aneurysm in association with peripheral venous thrombosis. Case presentation A previously healthy 23-year-old Saudi woman presented with massive hemoptysis a day prior to her admission to our hospital. She had a six-month history of recurrent fever cough dyspnea and recurrent oral ulceration. Contrast-enhanced computed tomography scan of her chest and pulmonary angiogram demonstrated a single right-lower lobe pulmonary artery aneurysm. She underwent thoracotomy and right lower lobe resection. Her postoperative course was complicated by deep vein thrombosis. She also developed headache and papilledema while a magnetic resonance imaging of her brain suggested vasculitis. Based on these clinical presentations she was diagnosed and treated with Hughes-Stovin syndrome. Conclusion The majority of cases of Hughes-Stovin syndrome are reported among men with only two cases occurring in women. A case of Hughes-Stovin syndrome occurring in a woman is presented in this report. She was treated successfully with multimodality treatment that includes surgery steroids and cytotoxic agents. Introduction The combination of pulmonary artery aneurysm and thromboembolic disease is uncommon but is reported in association with Behcet s disease 1-5 . The disease affects mainly adults especially men 1-3 . It is prevalent in Japan the Middle East and the Mediterranean but it is also found worldwide 1-4 . Behcet s disease is a form of systemic vasculitis affecting mainly the .