tailieunhanh - Báo cáo y học: " Renal cancer associated with recurrent spontaneous pneumothorax in Birt-Hogg-Dubé syndrome: a case report and review of the literature"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài:Renal cancer associated with recurrent spontaneous pneumothorax in Birt-Hogg-Dubé syndrome: a case report and review of the literature | Warwick et al. Journal of Medical Case Reports 2010 4 106 http content 4 1 106 Ws CASE REPORTS CASE REPORT Open Access Renal cancer associated with recurrent spontaneous pneumothorax in Birt-Hogg-Dubé syndrome a case report and review of the literature Geoffrey Warwick 1 Louise Izatt2 and Elizabeth Sawicka3 Abstract Introduction Birt-Hogg-Dubé syndrome is a rare genodermatosis characterized by hair follicle hamartomas renal tumors and spontaneous pneumothorax. We present the case of a patient with pulmonary cysts and recurrent spontaneous pneumothorax. She had typical skin lesions and was found to have a hybrid oncocytoma which was surgically excised. Case presentation A 60-year-old Caucasian woman had a 10-year history of cystic lung disease and recurrent spontaneous pneumothoraces. She was noted to have papular lesions over her face and forehead. The result of a biopsy showed these lesions to be fibrofolliculomas. A diagnosis of Birt-Hogg-Dubé syndrome was made and she was screened for renal tumors since these are a recognized association. A hybrid oncocytoma was detected which was surgically excised by partial nephrectomy. Conclusion It is important to consider a possible diagnosis of Birt-Hogg-Dubé syndrome in cases of recurrent pneumothorax. Affected individuals must be screened for renal tumors a potentially lethal consequence of this syndrome. Introduction Birt-Hogg-Dubé syndrome BHDS is a rare genoderma-tosis characterized by hair follicle hamartomas renal tumors and spontaneous pneumothorax. We present the case of a 60-year-old Caucasian woman with pulmonary cysts and recurrent spontaneous pneumothoraces who had typical skin lesions. On screening she was found to have a hybrid oncocytoma which was surgically excised. A diagnosis of BHDS should be considered in cases of recurrent pneumothorax and affected individuals must be screened for renal tumors. Case presentation Our patient was a 60-year-old Caucasian .