tailieunhanh - Báo cáo y học: " Angiomyofibroblastoma of the spermatic cord: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Angiomyofibroblastoma of the spermatic cord: a case report | Tzanakis et al. Journal of Medical Case Reports 2010 4 79 http content 4 1 79 jAc JOURNALOF medical ÌỤr case REPORTS CASE REPORT Open Access Angiomyofibroblastoma of the spermatic cord a case report Nikolaos E Tzanakis1 George A Giannopoulos1 Stamatis P Efstathiou2 Georgios E Rallis1 Nikolaos I Nikiteas3 Abstract Introduction Angiomyofibroblastoma is a benign soft tissue tumor with tendency to arise in the vulva. Case presentation We report a 36-year-old Greek Caucasian man presenting with a left inguinal painless mass. This is the second case of angiomyofibroblastoma of the spermatic cord. At operation a cm well-circumscribed solid tumor was found adherent to the spermatic cord. The tumor consisted of spindle-shaped cells proliferating in short fascicles between numerous medium-sized blood vessels with thin and hyalinized walls. Neoplastic cells had eosinophilic cytoplasm with neither mitotic figures nor nuclear atypia. The stroma included abundant mast cells and few mature lypocytes. Immunostaining showed positivity for vimentin CD34 desmin and smooth muscle actin. Our patient was treated by simple excision and was followed up for five years with clinical examination and ultrasonography revealing no evidence of local recurrence or metastasis. Conclusion This unusual neoplasm should be distinguished from aggressive angiomyxoma and other myxoid malignant tumors with widespread metastatic potential. Introduction In 1992 Fletcher et al. 1 described 10 cases of a previously unrecognized benign soft tissue tumor of the vulva that was often misdiagnosed as aggressive angio-myxoma. The term angiomyofibroblastoma AMF was endorsed for this novel tumor. The morphologic hallmarks of this tumor were its well-circumscribed margins prominent vascularity and features suggestive of myofibroblastic differentiation 1 . Since the aforementioned original study there have been several additional reports of AMF of the genital tracts of both men 2 3 and .

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