tailieunhanh - Báo cáo hóa học: " Meningeal carcinomatosis diagnosed during stroke evaluation in the emergency department"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Meningeal carcinomatosis diagnosed during stroke evaluation in the emergency department | Cooney and Cooney International Journal of Emergency Medicine 2011 4 52 http content 4 1 52 o International Journal of Emergency Medicine a SpringerOpen Journal CASE REPORT Open Access Meningeal carcinomatosis diagnosed during stroke evaluation in the emergency department Derek R Cooney1 2 and Norma L Cooney1 2 Abstract A 70-year-old female presented to the emergency department with a 3-day history of intermittent dysphasia and right facial droop. Computed tomography CT and magnetic resonance imaging MRI were obtained and the patient was found to have meningeal carcinomatosis also known as leptomeningeal metastases. Meningeal carcinomatosis is a rare metastatic complication of some solid tumors and hematopoietic neoplasms and has a median survival rate of months. The role of the emergency physician is to appropriately diagnose this condition treat emergent side effects provide symptomatic relief and ensure multi-disciplinary management. Background Meningeal carcinomatosis MC also known as leptomeningeal metastases is a rare metastatic complication of some solid tumors and hematopoietic neoplasms 1 . Incidence in patients with a primary solid tumor is 4-15 2 . The median survival rate is around months with a rate of months for solid tumors and months for hematopoietic tumors 3 . The most commonly associated primary solid tumors are breast carcinoma 1234 lung carcinoma 10-26 and melanoma 17-25 2 . Although most patients found to have MC have a previously diagnosed primary neoplasm in a study by Clarke and colleagues published in 2010 as many as 916 of p atients were thought to be disease free until diagnosed with MC 3 . Case presentation A 70-year-old female presented to the emergency department with a 3-day history of intermittent dysphasia and right facial droop. The patient had just returned from an overseas flight the day prior to the onset of symptoms. There was no history of headache nausea vomiting or dizziness. Upon arrival the