tailieunhanh - Báo cáo y học: "CXCL10 blockade protects mice from cyclophosphamide-induced cystitis"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: CXCL10 blockade protects mice from cyclophosphamide-induced cystitis. | Journal of Immune Based Therapies and Vaccines BioMed Central Original research CXCL10 blockade protects mice from cyclophosphamide-induced cystitis Senthilkumar K Sakthivel 1 Udai P Singh 2 Shailesh Singh3 Dennis D Taub4 Kristian R Novakovic5 and James W Lillard Jr 3 6 Address Department of Pathology Emory University School of Medicine Atlanta GA USA 2Deparment of Pathology Microbiology and Immunology University of South Carolina School of Medicine Columbia SC 29208 USA 3Department of Microbiology and Immunology University of Louisville Louisville KY USA 4Laboratory of Immunology Gerontology Research Center National Institute on Aging Baltimore MD USA 5Department of Urology University of Louisville Louisville KY USA and 6Department of Microbiology Biochemistry and Immunology Morehouse School of Medicine Atlanta GA USA Email Senthilkumar K Sakthivel - ssakthi@ Udai P Singh - usingh@ Shailesh Singh - Dennis D Taub - taubd@ Kristian RNovakovic - krnova01@ James W Lillard Corresponding author fEqual contributors Open Access Published 28 October 2008 Received 9 July 2008 Journal of Immune Based Therapies and Vaccines 2008 6 6 doi l 476-8518-6-6 Accepted 28 October 2008 This article is available from http content 6 1 6 2008 Sakthivel et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Alterations in serum CXCR3 ligand levels were examined in interstitial cystitis IC patients similar expression patterns in serum as well as CXCR3 CXCR3 ligands and cytokines expressed by peripheral and local leukocyte subpopulations were characterized during cyclophosphamide CYP .