tailieunhanh - Báo cáo khoa hoc:" Severe generalised hypersensitivity reaction to topical neomycin after cataract surgery: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Severe generalised hypersensitivity reaction to topical neomycin after cataract surgery: a case report | Journal of Medical Case Reports BioMed Central Open Access Case report Severe generalised hypersensitivity reaction to topical neomycin after cataract surgery a case report Imran A Ansari and Ernest Onyema Address Department of Ophthalmology Princess Alexandra Hospital Harlow Essex UK Email Imran A Ansari - dociansari@ Ernest Onyema - eyemd121@ Corresponding author Published 23 February 2008 Received 9 July 2007 Journal of Medical Case Reports 2008 2 57 doi 1752-1947-2-57 Accepted 23 February 2008 This article is available from http content 2 1 57 2008 Ansari and Onyema licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Systemic hypersensitivity reactions to topical ophthalmic treatment occur rarely but when they do they can be severe as highlighted by this case. Case presentation A post-operative cataract surgery patient developed a severe and generalised hypersensitivity reaction following topical treatment with Maxitrol Dexamethasone and Neomycin eye drops. The patient reported a previous allergic reaction to Neomycin. Conclusion This case report emphasises the importance of a thorough drug and allergy history when patients are seen at pre-assessment or clerked in for surgery. Introduction Adverse external ocular effects of topical ophthalmic therapy have been estimated to occur in 10 of all adverse reactions 1 . Drug-related ocular allergies are often the result of type IV hypersensitivity reactions although type 1 and type 3 hypersensitivity reactions may also be involved 2 . Hypersensitivity to localised ocular therapy may involve a localised contact reaction which may include itching redness tearing mucopurulent discharge and papillary .