tailieunhanh - Bóa cáo y học: "RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: a cohort analysis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care cung cấp cho các bạn kiến thức về ngành y đề tài: RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: a cohort analysis. | Available online http content 10 3 R73 Research RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients a cohort analysis Eric AJ Hoste1 2 Gilles Clermont1 Alexander Kersten1 Ramesh Venkataraman1 Derek C Angus1 Dirk De Bacquer3 and John A Kellum1 1The Clinical Research Investigation and Systems Modeling of Acute Illness CRISMA Laboratory Department of Critical Care Medicine University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA intensive Care Unit Ghent University Hospital Gent Belgium 3Department of Public Health Ghent University Gent Belgium Corresponding author John A Kellum kellumja@ Received 10 Mar 2006 Revisions requested 27 Mar 2006 Revisions received 1 Apr 2006 Accepted 1 0 Apr 2006 Published 12 May 2006 Critical Care 2006 10 R73 doi cc4915 This article is online at http content 10 3 R73 2006 Hoste et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction The lack of a standard definition for acute kidney injury has resulted in a large variation in the reported incidence and associated mortality. RIFLE a newly developed international consensus classification for acute kidney injury defines three grades of severity - risk class R injury class I and failure class F - but has not yet been evaluated in a clinical series. Methods We performed a retrospective cohort study in seven intensive care units in a single tertiary care academic center on 5 383 patients admitted during a one year period 1 July 200030 June 2001 . Results Acute kidney injury occurred in 67 of intensive care unit admissions with maximum RIFLE class R class I and class F in 12 27 and 28 respectively. Of the 1 510