tailieunhanh - Báo cáo y học: "Solute removal during continuous renal replacement therapy in critically ill patients: convection versus diffusion"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care cung cấp cho các bạn kiến thức về ngành y đề tài: Solute removal during continuous renal replacement therapy in critically ill patients: convection versus diffusion. | Available online http content 10 2 R67 Research Solute removal during continuous renal replacement therapy in critically ill patients convection versus diffusion Zaccaria Ricci1 Claudio Ronco2 Alessandra Bachetoni3 Giuseppe D amico4 Stefano Rossi4 Elisa Alessandri1 Monica Rocco1 and Paolo Pietropaoli5 Department of Intensive Care Policlinico Umberto I Rome Italy department of Nephrology Dialysis and Transplantation St Bortolo Hospital Vicenza Italy 3Laboratory of Clinical Chemistry Policlinico Umberto I Rome Italy department of Intensive Care Policlinico Umberto I Rome Italy department of Intensive Care Policlinico Umberto I Rome Italy Corresponding author Zaccaria Ricci Received 31 Jan 2006 Revisions requested 23 Jan 2006 Revisions received 14 Mar 2006 Accepted 19 Mar 2006 Published 28 Apr 2006 Critical Care 2006 10 R67 doi cc4903 This article is online at http content 10 2 R67 2006 Ricci et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction The best modality for continuous renal replacement therapy CRRT is currently uncertain and it is poorly understood how transport of different solutes whether convective or diffusive changes over time. Methods We conducted a prospective cross over study in a cohort of critically ill patients comparing small urea and creatinine and middle P2 microglobulin molecular weight solute clearance filter lifespan and membrane performance over a period of 72 hours during 15 continuous veno-venous dialysis CVVHD and 15 continuous veno-venous hemofiltration CVVH sessions. Both modalities were administered based on a prescription of 35 ml kg h and using polyacrylonitrile filters. Results Median filter lifespan was .