tailieunhanh - Báo cáo khoa hoc:" Leiomyosarcoma of the skin with osteoclast-like giant cells: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Leiomyosarcoma of the skin with osteoclast-like giant cells: a case report | Journal of Medical Case Reports BioMed Central Case report Open Access Leiomyosarcoma of the skin with osteoclast-like giant cells a case report Deba P Sarma Eric E Santos and Bo Wang Address Department of Pathology Creighton University Medical Center Omaha NE 68131 USA Email Deba P Sarma - debasarma@ Eric E Santos - pyaar474@ Bo Wang - bowang@ Corresponding author Published 14 December 2007 Received 28 June 2007 Journal of Medical Case Reports 2007 1 180 doi 1752-1947-1-180 Accepted 14 December 2007 This article is available from http content 1 1 180 2007 Sarma et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Osteoclast-like giant cells have been noted in various malignant tumors such as carcinomas of pancreas and liver and leiomyosarcomas of non-cutaneous locations such as uterus and rectum. We were unable to find any reported case of a leiomyosarcoma of the skin where osteoclast-like giant cells were present in the tumor. Case presentation We report a case of a 59-year-old woman with a cutaneous leiomyosarcoma associated with osteoclast-like giant cells arising from the subcutaneous artery of the leg. The nature of the giant cells is discussed in light of the findings from the immunostaining as well as survey of the literature. Conclusion A rare case of cutaneous leiomyosarcoma with osteoclast-like giant cells is reported. The giant cells in the tumor appear to be reactive histiocytic cells. Introduction Osteoclast-like giant cells have been noted in various malignant tumors such as carcinomas of pancreas and liver and leiomyosarcomas of non-cutaneous locations such as uterus and rectum. We were unable to find any reported .