tailieunhanh - Báo cáo khoa hoc:" An unusual exacerbation of chronic obstructive pulmonary disease (COPD) with herpes simplex tracheitis: case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: An unusual exacerbation of chronic obstructive pulmonary disease (COPD) with herpes simplex tracheitis: case report | Journal of Medical Case Reports BioMed Central Case report Open Access An unusual exacerbation of chronic obstructive pulmonary disease COPD with herpes simplex tracheitis case report Alison C Boland Elizabeth H Iveson and Mark W Elliott Address Department of respiratory medicine St James s university hospital Leeds UK Email Alison C Boland - Elizabeth H Iveson - liziveson@ Mark W Elliott - Corresponding author Published 19 September 2007 Received 18 March 2007 _ . - - lrtl .A I ift 1-7 1 -7 101 Accepted 19 September 2007 Journal of Medical Case Reports 2007 1 91 doi 1752-1947-1-91 This article is available from http content 1 1 91 2007 Boland et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Chronic obstructive pulmonary disease COPD is a common cause of morbidity in the UK and is increasingly seen in elderly patients often requiring multiple courses of steroids. We present a case of a 72 year old lady with repeated exacerbations of COPD which did not respond to conventional treatment. Herpes simplex virus HSV1 tracheobronchitis was diagnosed following a rigid bronchoscopy and her symptoms improved with intravenous acyclovir. This is the first published case of HSV tracheitis in a non immunosuppressed individual with chronic lung disease. Background Herpes simplex virus HSV1 infection may be considered in the differential diagnosis of patients with chronic lung disease not responding to conventional treatment. This infection is a rare but potentially treatable cause of exacerbations in such patients. Appropriate diagnostic studies should be performed to confirm the diagnosis and initiate therapy .