tailieunhanh - Báo cáo khoa hoc:" Recurrence of hepatitis C virus during leucocytopenia and spontaneous clearance after recovery from cytopenia: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Recurrence of hepatitis C virus during leucocytopenia and spontaneous clearance after recovery from cytopenia: a case report | Journal of Medical Case Reports BioMed Central Case report Open Access Recurrence of hepatitis C virus during leucocytopenia and spontaneous clearance after recovery from cytopenia a case report Norbert H Gruener Bijan Raziorrouh and Maria-Christina Jung Address Medical Department II Klinikum Grofihadern Ludwig-Maximilians-University Munich Germany Email Norbert H Gruener - Bijan Raziorrouh - Maria-Christina Jung - Corresponding author Published 4 December 2007 Received 28 August 2007 Journal of Medical Case Reports 2007 1 169 doi 1752-1947-1-169 Accepted 4 December 2007 This article is available from http content 1 1 169 2007 Gruener et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction There is little information about the risk of HCV recurrence in immunosuppressed patients. Although the presence of antibodies to HCV and the absence of HCV-RNA is usually considered to indicate viral elimination the virus may not be completely eliminated but may be under control of an effective immune response. Case presentation A 69 year old man presented with jaundice elevated ALT AST lipase and concomitant abdominal pain. He was found to be positive for HCV-RNA genotype 3a and was diagnosed with acute hepatitis C. Six weeks later no HCV-RNA was detected and the patient was diagnosed with hyperthyreosis and started on propylthiouracil. After 4 weeks of propylthiouracil treatment the patient developed leucocytopenia followed by liver function deterioration and reappearance of HCV-RNA. Propylthiouracil was discontinued and his leukocyte counts increased. Twenty-eight .

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