tailieunhanh - Báo cáo y học: " Benzocaine and lidocaine induced methemoglobinemia after bronchoscopy: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Benzocaine and lidocaine induced methemoglobinemia after bronchoscopy: a case report. | Journal of Medical Case Reports BioMed Central Open Access Case report Benzocaine and lidocaine induced methemoglobinemia after bronchoscopy a case report Sophie Kwok Jacqueline L Fischer and John D Rogers Address Department of Internal Medicine University of Illinois College of Medicine at Peoria Peoria Illinois USA Email Sophie Kwok - sophiekwok@ Jacqueline L Fischer - jlf@ John D Rogers - jdr64@ Corresponding author Published 23 January 2008 Received 20 March 2007 Journal of Medical Case Reports 2008 2 16 doi 1752-1947-2-16 Accepted 23 January 2008 This article is available from http content 2 1 16 2008 Kwok et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Methemoglobinemia is a rare cause of hypoxemia characterized by abnormal levels of oxidized hemoglobin that cannot bind to and transport oxygen. Case presentation A 62-year-old male underwent bronchoscopy where lidocaine oral solution and Hurricaine spray 20 benzocaine were used. He developed central cyanosis and his oxygen saturation was 85 via pulse oximetry. An arterial blood gas revealed pH PCO2 42 PO2 282 oxygen saturation 85 . Co-oximetry performed revealed a methemoglobin level of normal . The patient was continued on 15 L minute nonrebreathing face mask and subsequent oxygen saturation improved to 92 within two hours. With hemodynamic stability and improved SpO2 treatment with methylene blue was withheld. Conclusion Methemoglobinemia is a potentially lethal condition after exposure to routinely used drugs. Physicians should be aware of this complication for early diagnosis and treatment. Introduction Methemoglobinemia is an uncommon 1 2 but potentially fatal