tailieunhanh - Báo cáo y học: "Pancytopenia due to iron deficiency worsened by iron infusion: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Pancytopenia due to iron deficiency worsened by iron infusion: a case report. | Journal of Medical Case Reports BioMed Central Case report Open Access Pancytopenia due to iron deficiency worsened by iron infusion a case report Apar Kishor Ganti 1 2 Nicole A Shonka3 and William D Haire1 Address department of Internal Medicine Division of Oncology Hematology University of Nebraska Medical Center Omaha NE USA 2VA Medical Center Omaha NE USA and department of Internal Medicine University of Nebraska Medical Center Omaha NE USA Email Apar Kishor Ganti - aganti@ Nicole A Shonka - nshonka@ William D Haire - whaire@ Corresponding author Published 7 December 2007 Received 3 July 2007 _c . ._ - __ J_. I irt i-7r- 10 -7 I 1-71- Accepted 7 December 2007 Journal of Medical Case Reports 2007 1 175 doi 1752-1947-1-175 r This article is available from http content 1 1 175 2007 Ganti et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Iron deficiency anemia is commonly associated with thrombocytosis although thrombocytopenia has been reported in occasional patients with iron-deficiency anemia. Much less common is the development of thrombocytopenia following replenishment of iron stores. Case Presentation We present the unusual case of a 39 year old African American female Jehovah s Witness who presented with a 10 month history of menorrhagia and pancytopenia. Laboratory investigations confirmed a severe iron deficiency. Since blood transfusion was unacceptable to her she was started on intravenous iron replacement therapy. This precipitated a sudden drop in both her platelet and white blood cell counts. Histopathological examination of the bone marrow revealed a hypercellular marrow with orderly trilineage hematopoiesis iron deficiency